Race : Human
Weapon : Twin Blades
Japanese VA: Katsuyuki Konishi
English VA : Scott Menville
Character Designer : Kousuke Fujishima
Once but a simple country boy, Lloyd is thrust out into a journey of epic proportions following a brutal attack on his village. The Chosen of Regeneration, Colette, is in fact one of his dearest friends, and after an exile from his home, Lloyd joins her on her Journey of Regeneration. Although the young warrior himself plays no part in the prophecy as such, he is still a strong optimist and eventually a fair leader.

Race : Human | Angel
Weapon : Chakram
Japanese VA: Nana Mizuki
English VA : Heather Hogan
Character Designer : Kousuke Fujishima
The kind and selfless Chosen of Regeneration from the land of Sylvarant, whose destiny is to climb the Tower of Salvation and restore life to the planet. For the sake of this cause, she would willingly give up her own life. She strongly believes in the Goddess Martel and wishes for the worlds of Sylvarant and Tethe'alla to be at peace.

Race : Half-elf
Weapon : Kendama
Japanese VA: Ai Orikasa
English VA : Colleen O'Shaughnessey
Character Designer : Kousuke Fujishima
A childhood friend of Lloyd who grew up studying magic in the small countryside village of Iselia. Being something of a prodigy with his powers, this young boy becomes an invaluable member of the Chosen's group through their Journey of Regeneration.

Race : Half-elf
Weapon : Rod
Japanese VA: Yumi Touma
English VA : Kari Wahlgren
Character Designer : Kousuke Fujishima
A skilled healer who worked as a teacher in Iselia before leaving with Colette on the Journey of Regeneration. Together with her younger brother Genis, she claims to be an orphaned elf who carved out a life in the land of Sylvarant.

Race : Human
Weapon : Sword | Dagger
Japanese VA: Fumihiko Tachiki
English VA : Cam Clarke
Character Designer : Kousuke Fujishima
A sword-wielding mercenary whom the Church of Martel hires in order to protect the Chosen on her Journey of Regeneration. At the beginning of the story, not much is known about this mysterious character, but as things progress, more and more of his history becomes clear.

Race : Human
Weapon : Cards
Japanese VA: Okamura Akemi
English VA : Jennifer Hale
Character Designer : Kousuke Fujishima
A female ninja from the Tethe'alla village of Mizuho who was sent to Sylvarant to assassinate Colette. However, as she travels through the faraway land, she begins to feel sympathy for its people and their plight.

Race : Human
Weapon : Sword | Dagger
Japanese VA: Masaya Onosaka
English VA : Shiloh Strong
Character Designer : Kousuke Fujishima
The Chosen of Mana from the land of Tethe'alla. Raised as an aristocrat in Meltokio, his view of the world is clouded. He is unaware of the effects of discrimination in his world, although he is aware of its presence. An irrepressible flirt, he takes every chance he can get to hit on all female party members, much to the annoyance of the party. Although he boldly displays an extroverted personality, he does not share his inner thoughts to others.

Race : Human
Weapon : Axe
Japanese VA: Houko Kuwashima
English VA : Tara Strong
Character Designer : Kousuke Fujishima
A young girl who is a victim to the effects of a special Exsphere, halting her physical growth. She is very quiet and constantly asserts her need to go home, but when she regains her true self, she slowly begins to act more human.

Race : Human
Weapon : Greaves
Japanese VA: Akio Ohtsuka
English VA : Crispin Freeman
Character Designer : Kousuke Fujishima
A convict bound with shackles for a crime he committed long ago, this man owes no real debt to society for what he did, yet he is unable to forgive himself. The party first meets Regal in the Meltokio sewers, and he seems to know Presea from somewhere.

Race : Half-elf
Japanese VA: Minami Takayama
English VA : Brianne Siddall
Character Designer : Kousuke Fujishima
A young half-elf outcast from Ozette, he befriends the party after Cruxis destroys the village. Being so close to Genis's age, they quickly bond. The party shows Mithos that it is possible for humans and half-elves to work together. He is named after Mithos the Hero.